Ascending aorta backward flow parameters estimated from phase-contrast cardiovascular magnetic resonance: new indices of vascular aging
نویسندگان
چکیده
Methods One hundred healthy subjects (50 women, mean age: 40 ±15 years (19-79 years) were studied. Aortic stiffness (aortic arch pulse wave velocity PWVAO, AA distensibility), aortic arch geometry (AA diameter and arch length) and parameters related to AA global backward and forward flows (volume, flow rate peak, and onset time) were estimated from CMR. Carotid-femoral pulse wave velocity (PWVCF), as well as reflection parameters such as carotid augmentation index (AIx) and time to return of the reflected pressure wave (Ti) were assessed by tonometry.
منابع مشابه
Ascending aorta backward flow parameters estimated from phase-contrast cardiovascular magnetic resonance data: new indices of arterial aging
Methods We studied 80 asymptomatic subjects without overt cardiovascular disease and free of significant aortic regurgitation (50 men, age: 42±17 years) who underwent cine and PC-CMR imaging of the thoracic aorta (1.5T) as well as carotid-femoral tonometry (PulsePen). Tonometry provided carotid-femoral pulse wave velocity (PWVCF), as well as reflection parameters such as carotid augmentation in...
متن کاملConsistency of aortic distensibility and pulse wave velocity estimates with respect to the Bramwell-Hill theoretical model: a cardiovascular magnetic resonance study
BACKGROUND Arterial stiffness is considered as an independent predictor of cardiovascular mortality, and is increasingly used in clinical practice. This study aimed at evaluating the consistency of the automated estimation of regional and local aortic stiffness indices from cardiovascular magnetic resonance (CMR) data. RESULTS Forty-six healthy subjects underwent carotid-femoral pulse wave ve...
متن کاملQuantification of aortic valve regurgitation by phase-contrast magnetic resonance in patients with bicuspid aortic valve: where to measure the flow?
Background Phase-contrast magnetic resonance (PC-MR) is used to quantify the aortic regurgitation (AR) by measuring the forward and backward flow in the ascending aorta (AAo), thereby quantifying the regurgitant fraction. Patients with bicuspid aortic valve (BAV) have an eccentric systolic aortic flow jet, causing an abnormal flow in the AAo. Therefore, we hypothesized that the flow measurement...
متن کاملIntraindividual validation of 4D flow measurement against 2D flow measurements in aortas with bicuspid or tricuspid valves by cardiovascular magnetic resonance (CMR)
Background Theoretically, blood flow in the ascending aorta of patients with helical flow patterns, as in patients with bicuspid aortic valves (BAV), are underestimated by routine two dimensional (2D) phase contrast velocity encoding (PC-VENC). Four dimensional (4D) PC-VENC is theoretically not influenced by flow patterns. Hence, both, 2D PC-VENC and 4D PC VENC should result in similar blood fl...
متن کاملEffect of Bias in Contrast Agent Concentration Measurement on Estimated Pharmacokinetic Parameters in Brain Dynamic Contrast-Enhanced Magnetic Resonance Imaging Studies
Introduction: Pharmacokinetic (PK) modeling of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is widely applied in tumor diagnosis and treatment evaluation. Precision analysis of the estimated PK parameters is essential when they are used as a measure for therapy evaluation or treatment planning. In this study, the accuracy of PK parameters in brain DCE...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2013